UroSense intend to engineer the current Foley catheter's streamline inner tubular surface so that it consists of irregularities in its texture.
By achieving this, bacteria will require more energy for biofilm formation - effectively reducing the surface area covered by biofilm per unit of time.
In turn, this will not only delay the development of biofilm, but will increase the catheter's lifetime.
BLADDER DAMAGE LIMITATION
A damaged mucosal lining increases the likelihood of bladder infection.
Today's Foley catheter is a primary cause for damaging the bladder's mucosa in catheterised patients, due to the location of its eye-hole. Upon urine drainage, due to pressure differences between the catheter lumen and the bladder, the suction created at the eye-hole can lead to traumatic contact with the bladder wall as its mucosal lining can also get sucked. This can leave haemorrhagic pseudopolyps and can potentially cause septicaemia.
UroSense are architecting an improved catheter tip and balloon construct, which aims to further limit bladder mucosal damage.
Urethral damage as a result of catheter insertion via the urethra is a prevalent issue. Multiple attempts are often required for adequate catheter placement, for which can be a stressful and traumatic experience for the patient.
Particularly, due to the male's challenging urethral anatomy, the main mechanisms for catheter urethral injury are:
i) inadvertent inflation of the balloon in the urethra
ii) creation of a false urethral passage due to excessive force on the catheter's tip when inserting the catheter
This can result in pockets of damaged urethral lining in which a CAUTI could develop.
UroSense aim to innovate the Foley catheter's catheter tip and balloon in order to tackle this issue.
It is all well and good having designed a catheter which tackles the current prevalent CAUTI causes. However, it is impractical if it is unaffordable.
Therefore, UroSense are on a mission to strike the balance between affordability and improved CAUTI rate outcomes, in view of making a realistic positive impact in a significant area of healthcare.